CVE-2025-12921

10.11.2025, 00:15

A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.

Injection

Provider	Type	Base Score	Atk. Vector	Atk. Complexity	Priv. Required	Vector
NIST	NIST	4.3 MEDIUM	NETWORK	LOW	LOW	CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:L/I:N/A:N
VulDB	CNA	4.3 MEDIUM				CVSS:3.0/AV:N/AC:L/PR:L/UI:N/S:U/C:L/I:N/A:N/E:P/RL:X/RC:R

Awaiting analysis

This vulnerability is currently awaiting analysis.

Base Score

CVSS 3.x

EPSS Score

Percentile: Unknown

Common Weakness Enumeration

CWE-74 - Improper Neutralization of Special Elements in Output Used by a Downstream Component ('Injection')
The software constructs all or part of a command, data structure, or record using externally-influenced input from an upstream component, but it does not neutralize or incorrectly neutralizes special elements that could modify how it is parsed or interpreted when it is sent to a downstream component.

References

https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md

https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md#poc

https://vuldb.com/?ctiid.331641

https://vuldb.com/?id.331641

https://vuldb.com/?submit.680872